Expansion of CD4+ cytotoxic T lymphocytes with specific gene expression patterns may contribute to suppression of tumor immunity in oral squamous cell carcinoma: single-cell analysis and in vitro experiments
Description
CONCLUSION: Our study provides a dynamic landscape of lymphocytes and demonstrates a systemic investigation of CD4^(+) CTL effects infiltrating into OSCC lesions, which may share some pathogenesis reported in severe T and B cell-activated diseases
