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PubMed COVID-19 Clinical Care

91 - 100 of 60079 results found

Human judgement forecasting of COVID-19 in the UK

Date
Monday, April 15, 2024 - 4:00 AM
Description
CONCLUSIONS: Human judgement forecasts and computational models can produce forecasts of similar quality for infectious disease such as COVID-19. The results of forecast evaluations can change depending on what metrics are chosen and judgement on

Predicting Functional Conformational Ensembles and Binding Mechanisms of Convergent Evolution for SARS-CoV-2 Spike Omicron Variants Using AlphaFold2 Sequence Scanning Adaptations and Molecular Dynamics Simulations

Date
Monday, April 15, 2024 - 4:00 AM
Description
In this study, we combined AlphaFold-based approaches for atomistic modeling of multiple protein states and microsecond molecular simulations to accurately characterize conformational ensembles and binding mechanisms of convergent evolution for the